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Scientific Committee on Consumer Products (SCCP)


Report Title: Preliminary Opinion on Safety of Nanomaterials in Cosmetic Products
Report ID: 191
Date: 6/19/2007
Author: Scientific Committee on Consumer Products (SCCP)
Report Type: Committee Report
URL: [sccp_o_099.pdf]
Country: European Union
Organization: Scientific Committee on Consumer Products (SCCP)
Summary: Following a report by the UK Royal Society and Royal Academy of Engineering which suggested treating nanomaterials as new chemicals and questioned the suitability of mass-based standards for assessing toxicological risks, the European Communitys Scientific Committee on Consumer Products (SCCP) was requested to examine the safety of nanomaterials in cosmetic products. These materials are either labile (disintegrating upon skin contact into their molecular components) or insoluble (such as titanium dioxide in sunscreen). Insoluble nanoparticles are the primary cause of concern for human safety. This committee report examines possible health concerns and exposure routes of these nanoparticles. The existing in vitro technique for estimating skin absorption may not be applicable to nanoscale materials, and the committee suggests that new methodologies are needed. One major problem is the need for in vivo testing to determine nanoparticle concentrations in organs, because of the ban upon animal testing for cosmetic products.
Archived Copy: SCCP (2007), Preliminary opinion on safety of nano_191_8431.pdf



Report Title: The SCCP'S Notes of Guidance for the Testing of Cosmetic Ingredients and Their Safety Evaluation, 6th Revision
Report ID: 164
Date: 12/19/2006
Author: European Union, Scientific Committee on Consumer Products
Report Type: Guidance Document
URL: [sccp_o_03j.pdf]
Country: European Union
Organization: Scientific Committee on Consumer Products (SCCP)
Summary: The document contains relevant information on the different aspects of testing and safety evaluation of cosmetic ingredients. It is designed to provide guidance to public authorities and cosmetic industry, in order to improve harmonized compliance with Directive 76/768/EEC 1 and in particular by the Sixth (Dir. 93/35/EEC) and Seventh (Dir. 2003/15/EC3) Amendments to this Directive. The "Notes of Guidance" are regularly revised and updated in order to incorporate the progress of scientific knowledge in general, and the experience gained in particular, in the field of testing and safety evaluation of cosmetic ingredients. Since the last revision, several new opinions of importance to the content of this guidance document have been adopted and they form the basis of this new revision. The Notes of Guidance should not be seen as a checklist, but have been compiled to provide assistance in the complex process of the testing and safety evaluation of cosmetic ingredients. As was also the case in the previous revision, individual SCCP opinions are not provided in detail, but are briefly summarized and clearly referred to. The revisions contained in this document focus on cosmetic products, with particular emphasis placed on testing guidelines and safety assessments.

Archived Copy: sccp_o_03j_164_5464.pdf



Report Title: Preliminary Opinion on Safety of Nanomaterials in Cosmetic Products
Report ID: 77
Date: 6/19/2007
Report Type: General Report
URL: [risk_en.htm]
Country: Other
Organization: Scientific Committee on Consumer Products (SCCP)
Summary: This opinion is a response by the SCCP to questions regarding the safety of nanomatierals in cosmetic products, the implications on animal testing, and whether previous opinions about nanomaterials currently used in sunscreen products would need to be revised. The opinion indicated that conventional risk assessment methodologies may be adequate for labile nanoparticles. However, it mentioned that primary health concerns involve insoluble particles but are inconclusive due to insufficient information at this time. Furthermore, the opinion stresses the need for new methodologies to assess percutaneous penetration pathways because evidence indicates that mechanical and/or chemical action on the skin may have an effect on nanoparticles penetration. This opinion also stated that large data gaps exist in the risk assessment of nanoparticles used in cosmetic products that are inhaled and ingested. In regards to animal testing, the opinion stated that only validated “in vitro” methods may be tested on animals, but currently there are no validated “in vitro” methods for nanomaterials. Finally, the opinion found that due to the considerable increase in available scientific data on nanosized particles it is necessary to review safety of nanomaterials currently used in sunscreen products.



 
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