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Report Title: Preliminary Analysis of Exposure Measurement and Exposure Mitigation in Occupational Settings: Manufactured Nanomaterials
Report ID: 535
Date: 4/17/2009
Author: OECD
Report Type: General Report
URL: [42594202.pdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD), as part of its efforts to ensure the safe development of nanotechnology, established a project on Exposure Measurement and Exposure Mitigation as a formal Steering Group of the OECD Working Party on Manufactured Nanomaterials at its third meeting in November 2007. The operational plan outlined three phases of work: Exposure in occupational settings, exposure to humans resulting from contact with consumer products and environmental releases of manufactured nanomaterials, and exposure to environmental species resulting from environmental releases of manufactured nanomaterials. The objectives of phase 1, which this document covers, were to identify and compile guidance information for exposure measurement and mitigation for manufactured nanomaterials in occupational settings and to analyze existing guidance information for its accuracy in addressing manufactured nanomaterials, identify issues, and prepare recommendations. This report provides a preliminary analysis of exposure measurement and summaries of background documents. Currently, there is no agreement on metrics of exposure to nanomaterials, and several organizations recommend a multifaceted approach with several sampling techniques for characterizing workplace exposure. Preliminary recommendations include providing guidance on appropriate metrics of exposure, providing recommendations on measurement techniques and sampling methods, identifying reference nanomaterials for quality control of exposure measurements, comparing workplace survey and sampling protocols, and identifying biomarkers of nanomaterial exposure.
Archived Copy: 42594202_535_3232.pdf



Report Title: OECD Environment, Health and Safety Publications Series on the Safety of Manufactured Nanomaterials, No. 25, Guidance Manual for the Testing of Manufactured Nanomaterials: OECD’s Sponsorship Programme; First Revision
Report ID: 520
Date: 6/2/2010
Report Type: Guidance Document
URL: [Default.htm]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: This document is the twenty-fifth in OECD's Health and Safety Publications series on manufactured nanomaterials. After its Workshop in December 2005, the OECD Working Party on Manufactured Nanomaterials created the Health and Safety Publications series. This document is intended to assist sponsors in the development of Dossier Development Plans (DDPs), which describe a testing program for nanomaterials. The Sponsorship Programme aims to determine essential safety information for manufactured nanomaterials. The OECD has created a list of fourteen representative nanomaterials and a list of areas for which information is needed, including physical-chemical properties, environmental fate, mammalian toxicology, and material safety. This Guidance Manual lists testing protocols and methodologies, and also describes the Sponsorship Programme in detail. The Programme is being organized in two phases; in the first, participants have been invited to sponsor the testing of a manufactured nanomaterial and prepare a DDP. In the second phase, participants determine, based upon a risk assessment of a nanomaterial, what additional testing is required and subsequently conduct testing in further depth. A two-year review of the first phase is expected to be completed in early 2011.
Archived Copy: JT03284642_520_9319.pdf



Report Title: OECD Environment, Health and Safety Publications Series on the Safety of Manufactured Nanomaterials, No. 22, OECD Programme on the Safety of Manufactured Nanomaterials 2009-2012: Operational Plans of the Projects
Report ID: 513
Date: 4/26/2010
Report Type: General Report
URL: [displaydocumentpdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD), as part of its efforts to ensure the safe development of nanotechnology, publishes the "Series on the Safety of Manufactured Nanomaterials" to provide information on its latest activities related to human health and environmental safety. This document is the 22th in a series of 25 publications (as of July 2010), and discusses the efforts of OECD's Working Party on Manufactured Nanomaterials. This report compiles the operational reports for 2009-2012 for the Working Party's eight projects: An OECD database on manufactured nanomaterials, safety testing of a representative set of manufactured nanomaterials, manufactured nanomaterials and test guidelines, cooperation on voluntary schemes and regulatory programmes, cooperation on risk assessment, the role of alternative test methods in nanotoxicology, cooperation on exposure measurement and exposure mitigation, and the environmentally sustainable use of manufactured nanomaterials. For each of these projects, this document lists the main objectives, work already accomplished, expected outputs for 2009-2012, and the outcome from past activities. The first phases of many of these projects are already underway and are returning valuable data, particularly in the area of safety.
Archived Copy: oecd_513_6932.pdf



Report Title: OECD Environment, Health and Safety Publications Series on the Safety of Manufactured Nanomaterials, No. 23, Report of the Questionnaire on Regulatory Regimes for Manufactured Nanomaterials
Report ID: 512
Date: 11/1/2009
Report Type: General Report
URL: [displaydocumentpdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: One of the projects of the OECD's Working Party on Manufactured Nanomaterials is the project on cooperation on voluntary schemes and regulatory programmes. The project has two objectives: to identify applicable regulatory regimes and how they address information requirements, hazard identification, exposure mitigation, risk assessment, and risk management measures; and to provide an indication of regulatory activity and trends over time through the gathering of information on nanomaterial notifications provided for in various regulatory schemes. This report contains the responses from legislations to a questionnaire which was sent out on July 28, 2008. Twenty-four responses were received; none of these reported having legislation specific to nanomaterials, but most indicated that current legislation had authority to regulate nanomaterials. Fourteen legislations reported having pre-market notification and assessment of substances, and eight of those did not have any trigger quantities for registration or notification. This document contains the responses from all twenty-four legislations.
Archived Copy: oecd2_512_9223.pdf



Report Title: OECD Environment, Health and Safety Publications Series on the Safety of Manufactured Nanomaterials, No. 20, Current Development/Activities on the Safety of Manufactured Nanomaterials – Tour de Table at the 6th Meeting of the Working Party on Manufactured Nanomaterials
Report ID: 509
Date: 2/24/2010
Report Type: Meeting Minutes
URL: [44947758.pdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: This document contains information shared at the OECD's Working Party on Manufactured Nanomaterials 6th Meeting in October 2009, and is intended to provide stakeholders with a snapshot of information on activities relating to manufactured nanomaterials. The OECD's database of research projects is currently in production and has 732 projects as of November 1, 2009. The Working Party is currently evaluating remaining gaps in the database. In the area of safety testing, 14 countries have committed to funding and participating the OECD's nanomaterials testing programme. Other projects such as the review of test guidelines and examination of voluntary reporting schemes are underway and are expected to have publicly available results shortly. The OECD has also held a workshop on risk assessment (in September 2009), from which a document will be produced listing critical issues in the risk assessment of manufactured nanomaterials. The Working Party is also cooperating with other organizations such as the ISO and joined in the 2nd International Conference on Chemicals Management. This document additionally contains the responses from delegations in attendance at the 6th Meeting.
Archived Copy: 44947758_509_2724.pdf



Report Title: OECD Environment, Health and Safety Publications Series on the Safety of Manufactured Nanomaterials, No. 19, Analysis of Information Gathering Initiatives on Manufactured Nanomaterials
Report ID: 506
Date: 11/24/2009
Report Type: General Report
URL: [displaydocumentpdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD), as part of its efforts to ensure the safe development of nanotechnology, publishes the "Series on the Safety of Manufactured Nanomaterials" to provide information on its latest activities related to human health and environmental safety. This document is the 19th in a series of 25 publications (as of July 2010), and discusses the efforts of OECD's Working Party on Manufactured Nanomaterials. The Working Party was created in 2006 to help OECD member countries effectively address the safety challenges posed by nanomaterials. An analysis of current information gathering initiatives shows that while many countries have similar schemes, there are differences in confidentiality and scope, among others. Voluntary information gathering schemes should also be supplemented with mandatory schemes. Section II of the document summarizes the different schemes in use in Australia, Canada, Denmark, Germany, Ireland, the UK, and the US.
Archived Copy: oecd_506_3822.pdf



Report Title: OECD Database on Research into the Safety of Manufactured Nanomaterials
Report ID: 504
Date: 4/1/2009
Report Type: Webpage
URL: [Default.htm]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The OECD launched its Database on Research into the Safety of Manufactured Nanomaterials on April 1, 2009. The database builds on the previous Woodrow Wilson International Center for Scholars "Nanotechnology Health and Environmental Implications: An Inventory of Current Research." It is intended to be a global resource which collects research projects addressing environmental, health, and safety issues of manufactured nanomaterials. With the database, OECD aims to identify research gaps and assist researchers in future collaborative efforts. The database is freely available to the public and searchable online. Contributors must be approved by the OECD Secretariat prior to uploading.
Archived Copy: database_504_9267.pdf



Report Title: Identification, Compilation and Analysis of Guidance Information for Exposure Measurement and Exposure Mitigation: Manufactured Nanomaterials
Report ID: 386
Date: 6/22/2009
Author: OECD Environment, Health and Safety Publications Environment Directorate Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology
Report Type: Advisory Report
Publication: Series on the Safety of Manufactured Nanomaterials Number 10
URL: [JT03267097.PDF]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The OECD Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology Joint Meeting decided to hold a Workshop on the Safety of Manufactured Nanomaterials in December 2005, in Washington, D.C. Based on the conclusions and recommendations of the Workshop [ENV/JM/MONO(2006)19] they recognized that it was essential to ensure the efficient assessment of manufactured nanomaterials so as to avoid adverse effects from the use of these materials in the short, medium and longer term. With this in mind, the OECD Council established the OECD Working Party on Manufactured Nanomaterials (WPMN) as a subsidiary body of the OECD Chemicals Committee. This program concentrates on international cooperation with respect to human health and environmental safety implications of manufactured nanomaterials (limited mainly to the chemicals sector), and aims to ensure that the approach to hazard, exposure and risk assessment is of a high, science-based, and internationally harmonized standard. This document is intended to provide information on the outcomes and developments of the WPMN related to the safety of manufactured nanomaterials. It compiles guidance information for exposure measurement and exposure mitigation for manufactured nanomaterials in occupational settings; and addresses their adequacy for manufactured nanomaterials. The Working Party endorsed this report at its 5th Meeting on March 2009.
Archived Copy: JT03267097_386_4208.pdf



Report Title: Nanotechnology: An Overview Based on Indicators and Statistics
Report ID: 207
Date: 6/25/2009
Author: Organisation for Economic Co-Operation and Development (OECD)
Report Type: Working Document
URL: [JT03267289.PDF]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: This working paper attempts to provide a comprehensive overview of nanotechnology development by examining indicators and statistics. Development is often poorly monitored and growth predictions suffer from incomplete data regarding the value-added contributions of nanotechnology. At present, development can be traced across time only through the use of publications and patent data. This document categorizes and analyzes patent data by country, sector, and other classification schemes. It also presents and analyzes nanotechnology publication data, market forecasts, and numerous other statistics. The Revealed Technological Advantage (RTA) metric is presented for nanotechnology development sub-areas (chemicals, biotechnologies, etc.) for assessing specialization profiles across countries. Despite the data presented in this document, it calls for the creation of better metrics and qualitative case studies for future monitoring of nanotechnology development.
Archived Copy: 43179651_207_7178.pdf



Report Title: Comparison of Guidance on Selection of Skin Protective Equipment and Respirators for Use in the Workplace: Manufactured Nanomaterials
Report ID: 204
Date: 6/19/2009
Author: Environment Directorate Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology
Report Type: Research Report
URL: [43289781.pdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The OECD Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology (the Joint Meeting) held a Special Session on the Potential Implications of Manufactured Nanomaterials for Human Health and Environmental Safety (June 2005). This was the first opportunity for OECD member countries, together with observers and experts, to begin to identify human health and environmental safety related aspects of manufactured nanomaterials.

As a follow-up, the Joint Meeting decided to hold a Workshop on the Safety of Manufactured Nanomaterials in December 2005. The main objective was to determine the "state of the art" for the safety assessment of manufactured nanomaterials with a particular focus on identifying future needs for risk assessment within a regulatory context. Based on the conclusions and recommendations of the Workshop [ENV/JM/MONO(2006)19] it was recognized as essential to ensure the efficient assessment of manufactured nanomaterials so as to avoid adverse effects from the use of these materials. With this in mind, the OECD Council established the OECD Working Party on Manufactured Nanomaterials (WPMN) as a subsidiary body of the OECD Chemicals Committee. This program concentrates on human health and environmental safety implications of manufactured nanomaterials (limited mainly to the chemicals sector), and aims to ensure that the approach to hazard, exposure and risk assessment is of a high, science-based, and internationally harmonized standard.

This document is intended to provide information on activities of the WPMN related to the safety of manufactured nanomaterials. The Working Party endorsed this report at its 5th Meeting on March 2009. This document is published on the responsibility of the Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology of the OECD.
Archived Copy: 43289781_204_5604.pdf



Report Title: Report of an OECD Workshop on Exposure Assessment and Exposure Mitigation: Manufactured Nanomaterials
Report ID: 203
Date: 7/7/2009
Author: Environment Directorate; Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology
Report Type: Research Report
URL: [43290538.pdf]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The OECD Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology held a special session on June 2005 on the potential implications of manufactured nanomaterials for human health and environmental safety. This was the first opportunity for OECD member countries, together with observers and invited experts, to begin to identify human health and environmental safety related aspects of manufactured nanomaterials. As a follow-up, these groups held a workshop on the safety of manufactured nanomaterials the following December. The main objective was to determine the "state of the art" for the safety assessment of manufactured nanomaterials with a particular focus on identifying future needs for risk assessment within a regulatory context.

Based on the conclusions and recommendations of the Workshop [ENV/JM/MONO(2006)19] it was recognized as essential to ensure the efficient assessment of manufactured nanomaterials so as to avoid adverse effects from the use of these materials. With this in mind, the OECD Council established the OECD Working Party on Manufactured Nanomaterials (WPMN) as a subsidiary body of the OECD Chemicals Committee. This program concentrates on human health and environmental safety implications of manufactured nanomaterials, and aims to ensure that the approach to hazard, exposure and risk assessment is of a high, science-based, and internationally harmonized standard.

This document is the report of the Workshop on Exposure Assessment and Exposure Mitigation, which was held in October 2008. It intends to provide information on the outcomes and discussions of the WPMN related to the safety of manufactured nanomaterials. The opinions expressed in this document are those of the participants to the workshop and do not necessarily reflect the official views of the Organization or of the governments of its member countries.
Archived Copy: 43290538_203_8893.pdf



Report Title: Report of the OECDWorkshop on the Safety of Manufactured Nanomaterials: Building Co-operation, Co-ordination and Communication
Report ID: 184
Date: 4/28/2006
Author: Organisation for Economic Co-Operation and Development (OECD)
Report Type: Workshop Report
URL: [JT03208175.PDF]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: Following a Special Session on the Potential Implications of Manufactured Nanomaterials for Human Health and Environmental Safety on June 7, 2005, the OECD recognized the additional need to identify potential nanotechnology safety issues in detail and to relate those issues to short, medium, and long term actions which could be addressed within the scope of the OECDs Chemicals Programme. The OECD Workshop on the Safety of Manufactured Nanomaterials was held on December 7-9, 2005. Participants shared details of national safety-related activities and recommended the establishment of a permanent working group, the Working Group on the Risk Assessment and Management of Nanomaterials. This Workshop also supported databases, including the existing Woodrow Wilson database (storing investigations and peer-reviewed papers related to nanomaterial safety), for sharing existing knowledge of nanomaterial safety among all stakeholders. These database proposals were to be considered at the Business and Industry Advisory Committee to the OECD (BIAC)s next meeting in February 2006. The Workshop also encouraged closer cooperation with the ISO for standardization of definitions, characterization, and nomenclature of nanomaterials, by suggesting to the ISO particular focus areas where standardization would be most helpful.
Archived Copy: Michael Vincent OECD (2006), Joint Meeting of Chemicals Committee_184_2985.pdf



Report Title: Series on the Safety of Manufactured Nanomaterials, Number 6, List of Manufactured Nanomaterials and List of Endpoints for Phase One of the OECD Testing Programme
Report ID: 115
Date: 6/2/2008
Author: OECD
Report Type: Project Report
URL: [env-jm-mono(2008)13-rev]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD) is composed of representatives of 30 industralized countries who meet to address international policies and problems of economic development. The OECD's Working Party on Manufactured Nanomaterials aims to identify those nanomaterial properties which are relevant for safety testing. The Working Party's Safety Testing of a Representative Set of Manufactured Nanomaterials project identified a list of representative manufactured nanomaterials which are or will shortly be on the market. This document lists those nanomaterials, which include fullerenes, carbon nanotubes, silicon dioxide, etc. It also lists properties which the Project has determined are relevant to human safety testing. Such properties include, among others, surface chemistry, catalytic activity, particle size distribution, water solubility, porosity, and bioaccumulation potential. These lists will be utilized by the Working Party at a later date when developing methods for safety testing.



Report Title: OECD Work on the Safety of Manufactured Nanomaterials
Report ID: 112
Date: 8/1/2007
Author: OECD
Report Type: PowerPoint Presentation
URL: [37852382.ppt]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: This PowerPoint presentation highlights the various projects of the OECD in the area of nanotechnology safety. These are: The OECD Database on Safety Research, Research Strategies on Manufactured Nanomaterials, Safety Testing of a Representative Set of Manufactured Nanomaterials, Manufactured Nanomaterials and Test Guidelines, Co-operation on Voluntary Schemes and Regulatory Programmes, Co-operation on Risk Assessment, Alternative Methods in Nano Toxicology, and Exposure Measurement and Exposure Mitigation. For each project, this presentation contains a slide briefly describing the project, which country is chairing it, and the current status.



Report Title: Current Developments/Activities on the Safety of Manufactured Nanomaterials, Tour de Table at the 4th Meeting of the Working Party on Manufactured Nanomaterials
Report ID: 102
Date: 6/13/2008
Author: OECD
Report Type: Meeting Minutes
URL: [env-jm-mono(2008)29]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD) is composed of representatives of 30 industralized countries who meet to address international policies and problems of economic development. This document contains the information shared by member countries at the 4th meeting of the OECD's Working Party on Manufactured Nanomaterials. The Working Party, a subsidiary of the OECD's Chemicals Committee, meets periodically to share information regarding current developments in nanomaterial safety. Each delegation announced its current and planned national safety initiatives as well as present and future intergovernmental cooperation. Their announcements are sorted by country and summarized in this document.



Report Title: Current Developments/Activities on the Safety of Manufactured Nanomaterials, Tour de Table at the 2nd Meeting of the Working Party on Manufactured Nanomaterials
Report ID: 101
Date: 4/27/2007
Author: OECD
Report Type: Meeting Minutes
URL: [env-jm-mono(2007)16]
Country: Other
Organization: Organisation for Economic Co-Operation and Development (OECD)
Summary: The Organisation for Economic Co-Operation and Development (OECD) is composed of representatives of 30 industralized countries who meet to address international policies and problems of economic development. This document contains the information shared by member countries at the 2nd meeting of the OECD's Working Party on Manufactured Nanomaterials. The Working Party, a subsidiary of the OECD's Chemicals Committee, met to share information regarding current developments in nanomaterial safety. Each delegation announced its current and planned national safety initiatives as well as present and future intergovernmental cooperation. Their announcements are sorted by country and summarized in this document.



 
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